Lyophilisation, storage, and compound stability

Lyophilisation removes water under vacuum at low temperature, leaving a stable cake in the vial. In that state, most research peptides remain stable for extended periods when kept cold and away from light.

After reconstitution, stability drops sharply. Bacteriostatic water slows microbial growth but does not stop chemical degradation, so reconstituted material should be kept refrigerated and used within the window specified for the compound.

Repeated freeze-thaw cycles are the most common cause of degradation in laboratory settings. Aliquot once, then work from single-use portions.